I read and hear a lot of people talking about “fluctuating” hormones and that the fluctuations are what cause the mood swings women of every age experience. The term fluctuate means to change continually; shift back and forth; vary irregularly. This appears to many that this is what hormones do but the reality is hormones are not irregular. They are produced in a rhythmic fashion like the rhythm of the ocean tides and on a schedule of sorts. The term rhythm means movement or procedure with uniform or patterned recurrence of a beat like music. These “rhythm tides” can be measured, timed, and controlled to relative degree. As you can see from the chart attached, each hormone has it’s own rhythm of sheet music. These hormone tide cycles are what people refer to as fluctuations. They are to really be looked at as rhythms on a schedule.
It’s important to understand the significance of this phenomenon because it plays a critical role in in your hormone health and why you feel so crappy, and it’s not what you think. It’s not the “fluctuations” or the ups and downs of the peaks and valleys of your hormones that cause such a mess mentally and physically at any age, but rather the flattening of those peaks is what causes extreme mental and physical symptomology that many woman get diagnosed with disorders and conditions like bi-polar, fibromyalgia, endometriosis, osteoporosis, anxiety, depression, PMDD, PMS, and thousands of other conditions women are told they have to live with.
There are two critical peaks between estrogen and progesterone’s hormone tide cycles that have to be optimally maintained in order for a woman to feel alive and well. The follicular peak of estrogen at Days 12-13 dictates how all other hormones, including progesterone, will produce and function the rest of the menstrual cycle, provided you have healthy functioning ovaries. This follicular peak of estrogen, if high enough, will up regulate receptors not only for estrogen, but progesterone and all other hormones so they perform at optimal functionality. When this happens, progesterone is able to make its peak high enough to down regulate estrogen receptors so the lining of the uterus will shed for an incident-free menstrual experience.
It’s important to maintain these rhythmic peaks, not flatten them out. When they flatten, nothing in the brain or body of a woman will feel right, and she will begin the living decaying process to death. It sounds dramatic but that’s what happens. Your estrogen levels send signals to the body as to where you are in the reproductive life stage process, and when estrogen is low and remains low, the mind of the female, no matter her age, will want to check out so to speak and the mind and body will fall apart. It is estrogen that dictates all of this. Women are least susceptible to mental and physical conditions when estrogen is maintained at optimal levels with healthy peaks for receptor up regulation. Without receptor up regulation nothing works right, just mental and physical misery.
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Gnocchi D, Bruscalupi G. Circadian Rhythms and Hormonal Homeostasis: Pathophysiological Implications. Biology (Basel). 2017;6(1):10. Published 2017 Feb 4. doi:10.3390/biology6010010
Tsang AH, Barclay JL, Oster H. Interactions between endocrine and circadian systems. J Mol Endocrinol. 2014;52(1):R1-16.
Geary N, Asarian L. Cyclic estradiol treatment normalizes body weight and test meal size in ovariectomized rats. Physiol Behav. 1999;67(1):141-7.